Natamycin

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Natamycin

Natamycin or pimaricin (food additive Е235) is a strain produced in the fermentation process by the bacterium Streptomyces natalensis. Supplement Е235 slightly soluble in alcohol and water. However, natamycin is enough effective at very low concentrations. By its nature, natamycin is a natural antifungal agent and used in food industry as additive, preservative Е235.

Supplement Е235 non-toxic, but at high concentrations (500 mg / kg of body weight) may cause nausea, vomiting, and diarrhea. Being an antibiotic, Е235 additive is added to the food in a strictly limited quantity by the properties of the antibiotics kill not only the harmful fungi and bacteria, but the microorganisms involved in the life processes of the human body.

For decades Е235 preservative used in food industry to prevent the development of fungi in dairy products, meat and other food products. Supplement Е235 can also be used in confectionery products: cakes, cakes, biscuits. In addition, the Supplement is used Е235 in the manufacture of cheese, as its shell. As a result of surface treatment (irrigation of the surface or immersing in a solution of the finished product), preservative Е235 remain strictly on the surface of the cheese. In some countries it is allowed the use of natamycin for surface treatment of sausages.

In addition to the food industry natamycin is widely used in medicine in as a polyene antibiotic group macrolides for the treatment of fungal infections skin, mucous membranes, gastrointestinal tract. Natamycin is widely used in the treatment of external ear infections; candidiasis of skin and nails; of ringworm; intestinal candidiasis; fungal diseases of the oral cavity, such as acute and pseudomembranous acute atrophic candidiasis in patients with cachexia, immune insufficiency and other diseases caused by pathogenic yeast fungi. Of natamycin makes tablets, suspensions, cream, candles.

In many countries the use of additives Е235 in the food industry is strictly prohibited. In Ukraine pimaricin permitted for use in food products as additive, preservative Е235.

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